The Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce combines bold flavors and creamy textures, making it an ideal dish for gatherings or a cozy family dinner. This recipe is not only delicious but also simple to prepare, ensuring you can whip it up any night of the week. The unique blend of Cajun spices and rich garlic butter sauce makes this pasta dish stand out, delighting both your taste buds and your guests.
Why You’ll Love This Recipe
- Rich and Flavorful: The blend of Cajun seasoning and creamy cheeses creates a mouthwatering sauce that elevates the dish.
- Quick to Prepare: Ready in just 35 minutes, it’s perfect for busy weeknights or last-minute gatherings.
- Customizable: Adjust the spice level or add your favorite vegetables to suit your personal taste.
- Comfort Food: Creamy pasta dishes are always a hit; this one is no exception!
- Impressive Presentation: Garnished with fresh parsley and extra cheese, it looks as good as it tastes.

Tools and Preparation
Before diving into the cooking process, gather the necessary tools. Having everything ready will streamline your experience in making this delightful Cajun chicken rotini.
Essential Tools and Equipment
- Large pot
- Skillet
- Colander
- Measuring cups
- Wooden spoon
Importance of Each Tool
- Large pot: Essential for cooking the rotini pasta evenly and efficiently.
- Skillet: A must-have for searing the chicken and creating the delicious sauce.
- Colander: Perfect for draining the pasta without losing any precious noodles.
Ingredients
For the Chicken
- 1 lbs boneless, skinless chicken breasts, cut into bite-sized pieces
- 2 tbsp olive oil
- Salt and black pepper, to taste
- 1 tsp Cajun seasoning, adjust to taste
For the Pasta
- 12 oz rotini pasta
For the Sauce
- 3 tbsp unsalted butter, divided
- 4 cloves garlic, minced
- 1 cups heavy cream
- 1 cups shredded mozzarella cheese
- 1 cup freshly grated Parmesan cheese
- 1 tsp Italian seasoning
- Crushed red pepper flakes, to taste
For Garnish
- Fresh chopped parsley
How to Make Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce
Step 1: Boil the Pasta
Boil a large pot of salted water.
1. Add the rotini and cook until al dente, about 9-10 minutes.
2. Reserve ½ cup of the pasta water, then drain and set aside.
Step 2: Season the Chicken
Season the chicken pieces with Cajun seasoning, salt, and pepper.
1. Toss until evenly coated.
Step 3: Sear the Chicken
Heat olive oil and 1 tablespoon of butter in a large skillet over medium-high heat.
1. Add the chicken and sear for 7-8 minutes until golden brown and cooked through, stirring occasionally.
2. In the last minute, stir in half of the minced garlic to infuse flavor.
3. Remove chicken from skillet and set aside.
Step 4: Prepare the Sauce Base
Lower heat to medium.
1. Add remaining 2 tablespoons of butter to the same skillet along with the rest of the garlic.
2. Sauté for 30 seconds until fragrant.
Step 5: Create a Creamy Sauce
Pour in heavy cream while stirring as it heats.
1. Let it simmer for 2-3 minutes to thicken slightly.
Step 6: Incorporate Cheeses
Stir in mozzarella and Parmesan cheeses.
1. Mix well until melted into a thick, velvety sauce.
Step 7: Season Your Sauce
Season with Italian seasoning, crushed red pepper flakes (if using), salt, and pepper to taste.
Step 8: Combine Pasta with Sauce
Add cooked rotini to skillet.
1. Toss until all spirals are coated with that creamy Cajun cheese sauce.
2. Add a splash of reserved pasta water if needed to loosen sauce.
Step 9: Serve
Serve hot with Cajun garlic chicken spooned on top or folded in.
1. Garnish with fresh parsley and extra cheese if desired.
Enjoy your delightful Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce!
How to Serve Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce
Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce is a hearty and flavorful dish that can be enjoyed in various ways. Whether you want it as a main course or part of a larger meal, here are some serving suggestions to enhance your dining experience.
Pair with a Fresh Salad
- Caesar Salad – Crisp romaine lettuce, crunchy croutons, and creamy Caesar dressing complement the richness of the rotini.
- Garden Salad – A mix of fresh greens, tomatoes, cucumbers, and a light vinaigrette adds brightness to the meal.
Add Garlic Bread on the Side
- Classic Garlic Bread – Toasted bread topped with garlic butter pairs perfectly, allowing you to soak up the delicious sauce.
- Cheesy Garlic Bread – For extra indulgence, top your garlic bread with mozzarella cheese and bake until bubbly.
Serve with Roasted Vegetables
- Seasoned Roasted Broccoli – Toss broccoli florets with olive oil and seasoning for a healthy side that balances the creamy pasta.
- Mediterranean Roasted Veggies – Bell peppers, zucchini, and red onions roasted together add color and flavor to your plate.
How to Perfect Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce
To make your Cajun Chicken Rotini even more delightful, consider these helpful tips for perfecting this recipe.
- Use Fresh Ingredients – Fresh chicken and high-quality cheeses enhance flavor significantly.
- Adjust Spice Levels – If you enjoy heat, increase the Cajun seasoning or add more crushed red pepper flakes for an extra kick.
- Reserve Pasta Water – The starchy pasta water helps adjust the sauce’s consistency without losing flavor.
- Don’t Overcook the Pasta – Cooking until al dente ensures the pasta holds its shape and texture when mixed with the sauce.
- Mix Cheeses Thoroughly – Stirring in cheeses slowly helps achieve that creamy, velvety sauce without clumping.
- Garnish Generously – Fresh parsley not only looks beautiful but also adds a burst of freshness to every bite.
Best Side Dishes for Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce
Complementing your Cajun Chicken Rotini with a variety of side dishes can elevate your meal. Here are some excellent options to consider.
- Garlic Mashed Potatoes – Creamy mashed potatoes infused with garlic create a comforting pairing with the rich pasta.
- Corn on the Cob – Sweet corn provides a crunchy texture that contrasts beautifully with the creamy sauce.
- Coleslaw – A tangy coleslaw brings crunchiness and acidity that balances out the heaviness of the dish.
- Grilled Asparagus – Lightly seasoned asparagus adds elegance while keeping things fresh and healthy.
- Baked Sweet Potatoes – The natural sweetness of baked sweet potatoes complements the spicy chicken perfectly.
- Brussels Sprouts – Roasted Brussels sprouts offer a nutty flavor that pairs well with cheesy sauces.
Common Mistakes to Avoid
Cooking Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce can be a delightful experience, but there are common pitfalls to watch out for.
- Overcooking the Pasta: Cooking rotini beyond al dente can lead to mushy noodles. Always check your pasta a minute or two before the package suggests.
- Ignoring Seasoning: Under-seasoning the chicken might result in bland flavors. Ensure you evenly coat the chicken with Cajun seasoning and adjust according to taste.
- Not Using Enough Cheese: The creamy sauce relies on cheese for flavor. Don’t skimp on mozzarella and Parmesan; they make the dish irresistible!
- Skipping the Pasta Water: The reserved pasta water helps thicken the sauce. Always keep some aside before draining your rotini.
- Cooking at Too High a Heat: Searing chicken too aggressively can burn it. Use medium-high heat and monitor closely for even cooking.

Storage & Reheating Instructions
Refrigerator Storage
- Store leftovers in an airtight container.
- Consume within 3-4 days for best flavor and safety.
Freezing Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce
- Freeze in a freezer-safe container or bag.
- Best used within 2-3 months for optimal taste.
Reheating Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce
- Oven: Preheat to 350°F and heat covered for about 20 minutes, adding a splash of cream if needed.
- Microwave: Heat in short bursts, stirring often until warmed through. Add cream if necessary to maintain consistency.
- Stovetop: Warm over low heat in a skillet, adding reserved pasta water or cream to loosen the sauce.
Frequently Asked Questions
What is Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce?
Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce is a creamy pasta dish featuring seasoned chicken, rotini noodles, and a rich garlic butter sauce.
How can I customize this recipe?
You can add vegetables like bell peppers or spinach to enhance nutrition and flavor. Adjust spices based on your heat preference.
Can I use other types of cheese?
Yes! Feel free to experiment with different cheeses such as cheddar or gouda for unique flavors.
Is this recipe suitable for meal prep?
Absolutely! This dish stores well in the refrigerator or freezer, making it perfect for meal prepping ahead of time.
Final Thoughts
Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce is a wonderful blend of flavors and textures that makes mealtime exciting. Its creamy sauce pairs perfectly with tender chicken and spiraled pasta. Plus, customization options allow you to make it your own! Give this recipe a try; you won’t be disappointed!
Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce
Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce is a delightful fusion of creamy textures and bold flavors, perfect for a cozy family dinner or entertaining guests. This dish features tender chicken coated in zesty Cajun seasoning, tossed with rotini pasta, and enveloped in a luscious garlic butter sauce infused with rich mozzarella and Parmesan cheeses. Ready in just 35 minutes, it’s not only easy to prepare but also customizable to suit your taste preferences. Whether you serve it as a main course or alongside your favorite sides, this comforting pasta dish is sure to impress.
- Prep Time: 10 minutes
- Cook Time: 25 minutes
- Total Time: 35 minutes
- Yield: Serves 4
- Category: Dinner
- Method: Stovetop
- Cuisine: Cajun
Ingredients
- 1 lb boneless, skinless chicken breasts
- 12 oz rotini pasta
- 3 tbsp unsalted butter
- 4 cloves garlic
- 1 cup heavy cream
- 1 cup shredded mozzarella cheese
- 1 cup grated Parmesan cheese
- Cajun seasoning
- Fresh parsley for garnish
Instructions
- Boil pasta in salted water until al dente (9-10 minutes). Reserve ½ cup of pasta water, then drain.
- Season chicken pieces with Cajun seasoning, salt, and pepper.
- Heat olive oil and 1 tbsp butter in a skillet; sear chicken for 7-8 minutes until golden brown. Add half the minced garlic in the last minute.
- Remove chicken; lower heat and add remaining butter and garlic to the skillet. Sauté until fragrant.
- Stir in heavy cream and simmer to thicken (2-3 minutes).
- Mix in mozzarella and Parmesan cheeses until melted.
- Combine cooked rotini with sauce; adjust consistency with reserved pasta water if needed.
- Serve hot, garnished with parsley.
Nutrition
- Serving Size: 1 cup (230g)
- Calories: 590
- Sugar: 4g
- Sodium: 780mg
- Fat: 32g
- Saturated Fat: 17g
- Unsaturated Fat: 12g
- Trans Fat: 0g
- Carbohydrates: 49g
- Fiber: 2g
- Protein: 30g
- Cholesterol: 100mg
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